Other disorders of urea cycle metabolism (2025)

Table of Contents

Other disorders of urea cycle metabolism Endocrine, nutritional and metabolic diseasesNoteAll neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.Type 1 Excludestransitory endocrine and metabolic disorders specific to newborn (P70-P74) Metabolic disordersType 1 Excludesandrogen insensitivity syndrome (E34.5-)congenital adrenal hyperplasia (E25.0)hemolytic anemias attributable to enzyme disorders (D55.-)Marfan syndrome (Q87.4-)5-alpha-reductase deficiency (E29.1)Type 2 ExcludesEhlers-Danlos syndromes (Q79.6-) Other disorders of amino-acid metabolism Disorders of urea cycle metabolism Disorder of urea cycle metabolism, unspecified References

ICD-10-CM Codes
E00-E89
E70-E88
E72-
2025 ICD-10-CM Diagnosis Code E72.29

Other disorders of urea cycle metabolism

2016

2017

2018

2019

2020

2021

2022

2023

2024

2025

Billable/Specific Code

E72.29 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
The 2025 edition of ICD-10-CM E72.29 became effective on October 1, 2024.
This is the American ICD-10-CM version of E72.29 - other international versions of ICD-10 E72.29 may differ.

The following code(s) above E72.29 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to E72.29:

E00-E89
2025 ICD-10-CM Range E00-E89
Endocrine, nutritional and metabolic diseases
Note
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Type 1 Excludes
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Endocrine, nutritional and metabolic diseases
E70-E88
2025 ICD-10-CM Range E70-E88
Metabolic disorders
Type 1 Excludes
- androgen insensitivity syndrome (E34.5-)
- congenital adrenal hyperplasia (E25.0)
- hemolytic anemias attributable to enzyme disorders (D55.-)
- Marfan syndrome (Q87.4-)
- 5-alpha-reductase deficiency (E29.1)
Type 2 Excludes
- Ehlers-Danlos syndromes (Q79.6-)
Metabolic disorders
E72
ICD-10-CM Diagnosis Code E72
Other disorders of amino-acid metabolism
Type 1 Excludes
- disorders of:
- aromatic amino-acid metabolism (E70.-)
- branched-chain amino-acid metabolism (E71.0-E71.2)
- fatty-acid metabolism (E71.3)
- purine and pyrimidine metabolism (E79.-)
- gout (M1A.-, M10.-)
Other disorders of amino-acid metabolism
E72.2
ICD-10-CM Diagnosis Code E72.2
Disorders of urea cycle metabolism
Type 1 Excludes
- disorders of ornithine metabolism (E72.4)
Disorders of urea cycle metabolism

Approximate Synonyms

Congenital hyperammonemia, type i
Deficiency, carbamyl phosphate synthetase
Deficiency, n acetylglutamate synthetase
Hyperammonemia, type iii

ICD-10-CM E72.29 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

642 Inborn and other disorders of metabolism

Convert E72.29 to ICD-9-CM

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): No change
2022 (effective 10/1/2021): No change
2023 (effective 10/1/2022): No change
2024 (effective 10/1/2023): No change
2025 (effective 10/1/2024): No change

Diagnosis Index entries containing back-references to E72.29:

Disorder (of) - see also Disease
- urea cycle metabolism E72.20
  ICD-10-CM Diagnosis Code E72.20
  Disorder of urea cycle metabolism, unspecified
  2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Billable/Specific Code
  Applicable To
  Hyperammonemia
  Type 1 Excludes
  hyperammonemia-hyperornithinemia-homocitrullinemia syndrome E72.4
  transient hyperammonemia of newborn (P74.6)
  - other specified E72.29

ICD-10-CM Codes Adjacent To E72.29

E72.1 Disorders of sulfur-bearing amino-acid metabolism

E72.10 …… unspecified

E72.11 Homocystinuria

E72.12 Methylenetetrahydrofolate reductase deficiency

E72.19 Other disorders of sulfur-bearing amino-acid metabolism

E72.2 Disorders of urea cycle metabolism

E72.20 Disorder of urea cycle metabolism, unspecified

E72.21 Argininemia

E72.22 Arginosuccinic aciduria

E72.23 Citrullinemia

E72.29 Other disorders of urea cycle metabolism

E72.3 Disorders of lysine and hydroxylysine metabolism

E72.4 Disorders of ornithine metabolism

E72.5 Disorders of glycine metabolism

E72.50 Disorder of glycine metabolism, unspecified

E72.51 Non-ketotic hyperglycinemia

E72.52 Trimethylaminuria

E72.53 Primary hyperoxaluria

E72.59 Other disorders of glycine metabolism

E72.8 Other specified disorders of amino-acid metabolism

E72.81 Disorders of gamma aminobutyric acid metabolism

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

Other disorders of urea cycle metabolism (2025)

References

https://www.icd10data.com/icd10cm/codes/e00-e89/e70-e88/e72-/e72.29